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Our bodies have a way of actively regulating itself to maintain stable conditions necessary for survival; this is known as homeostasis. The endocannabinoid system (ECS) is a neuromodulatory system within our bodies that specifically interacts with cannabis to help achieve homeostasis. One function of homeostasis is the regulation of immune/inflammatory responses like cytokine inhibition, and release. For those of us with autoimmune disease, our own immune system attacks itself, causing chronic inflammation. The presence of proinflammatory cytokines are often a major contributor of inflammatory, and neuropathic pain. There is some evidence that suggests CBD can behave as a CB2 inverse agonist within our ECS to reduce, or inhibit an inflammatory response. That said, CBD has stronger antagonist properties when in the presence of THC. Hemp flower specifically, is rich in CBD, but carries a small amount of THC. This allows CBD to function at it's full potential. Cannabis flower is also also riiiiiich in chlorophyll. It's what makes it that beautiful green color we all adore, and love. Phytol, a component of chlorophyll, can significantly reduce pain by reducing/inhibiting proinflammatory cytokine release, and oxidative stress. Whole flower cannabis also contains terpenes. They have their own medicinal effects by interacting with cannabinoids, and phytonutrients. All of these things work in synergy many know as the "entourage effect". When we isolate cannabinoids, or other parts of cannabis; we're potentially disrupting the natural synergistic effect leading to reduced medicinal benefits. This principle has been my guide in how I medicate, and how I make my pain relief products at The Bitchy Hippie. So whether it's topical, oral, or smokable; utilizing whole flower cannabis/hemp goes beyond CBD, and THC for effective inflammatory pain relief. 

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Mar 5th 2022 Adriana RN

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